TWiV 1028: Asymptomatic SARS-CoV-2 infection and T cells

TWiV reviews approvals of the first gene therapy for severe hemophilia A in adults and a monoclonal antibody to prevent RSV respiratory disease in babies and toddlers, and a common allele of HLA that mediates asymptomatic SARS-CoV-2 infection through pre-existing T cell immunity due to previous exposure to common cold coronaviruses. Hosts: Vincent Racaniello, Dickson Despommier, Alan Dove, Kathy Spindler, and Brianne Barker Subscribe (free): Apple Podcasts, Google Podcasts, RSS, email Become a patron of TWiV! Links for this episode MicrobeTV Discord Server First gene therapy for hemophilia A approved (FDA) Luxurna, gene therapy for vision loss (FDA) Anti-RSV monoclonal antibody approved (FDA) Trial of single-dose Nirsevimab (NEJM) Letters read on TWiV 1028 Timestamps by Jolene. Thanks! Weekly Picks Dickson – Phoenix hits 110 degrees for the 19th day in a row, setting national record Brianne – James Webb Telescope One Year Anniversary Photo Kathy – Drone awards photos Alan – WHO Film Festival winners Vincent – Thinking, Fast and Slow by Daniel Kahneman Listener Picks David – The Mass Extinction Debates: A Science Communication Odyssey Intro music is by Ronald Jenkees Send your virology questions and comments to twiv@microbe.tv